ANTIDOTES TO REMEMBER


Too Much:                                                                                                       ADMINISTER:                                 

Valium                                                                                                                           flumazenil (Romazicon)
Antianxiety drugs

Opioids                                                                                                                         naloxone (Narcan)

Heparin                                                                                                                         Protamine sulfate
Anti-coagulants

Magnesium                                                                                                                  Calcium gluconate or Calcium Chloride

acetaminophen (Tylenol)                                                                                                acetylcysteine (Mucomyst)

alcohol                                                                                                                         naltrexone (ReVia)

anaesthesia & malignant hyperthermia                                                                           dantrolene sodium (Dantrium)

anaesthesia                                                                                                                 neostigmine (Prostigmin)

streptokinase – fibrinolytics                                                                                           aminocaproic acid (Amicar)

warfarin (Coumadin)                                                                                                      Vitamin K+ (Phytonadione)

Versed                                                                                                                       Flumazenil

Hypertensive Crisis                                                                                                      NiPride

Malignant hyperthermia                                                                                               Dantrolene (Dantirum)

Metabolic acidosis (diabetic)                                                                                        IV 0.9% NaCl to restore urine output to 30 – 60 mL/hr.  When BS goes
                                                                                                                                   down to 250, then 5% dextrose is added to fluid regimen.

K+                                                                                                                              Kayexalate (mild)

                                                                                                                                   HCO3 or albuterol (severe)

                                                                                                                                   Give insulin & IV glucose to put K+ back in cells

Phosphorus                                                                                                                  Diamox (diuretic)

                                                                                                                                   Hemodialysis (severe)

Extrapyramidal symptoms                                                                                             trihexyphenidyl (Artane)



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